Advanced Cryoscience is building an end-to-end biomedical cold chain to provide organs, tissues, and cell therapies on demand. Our non-toxic, DMSO-free cryoprotectant aims to enable indefinite storage at clinically practical high-subzero temperatures while preserving post-thaw function. We stack our cryoprotectants with portable subzero biotransportation devices, modular biobanking infrastructure for long-term storage, and a logistics hub to build a complete cold chain.