Apiary Therapeutics, founded by CCRM, Peter Zandstra, and Yale Michaels, is revolutionizing biologic delivery using off-the-shelf, stem cell-derived B cells. These engineered cells persist long-term, enabling continuous therapeutic production inside the patient. Our proprietary sense-and-respond gene circuits dynamically regulate therapy in response to disease. This approach offers a scalable, cost-effective solution for treating metabolic and infectious diseases, unlocking new possibilities for durable and affordable biologic therapies.